Preliminary Exploration of the Clinical Features and Immunological Correlation between TIGIT and Esophageal Squamous Cell Carcinoma

Objective: To analyze the relationship between TIGIT and clinical features of Esophageal Squamous Cell Carcinoma, we use transcriptomic data from TCGA database, to investigate immune microenvironment provide a basis for improving treatment strategy prognosis patients with Carcinoma. Methods: RNA sequencing corresponding cancer tissues were obtained database carcinoma, Carcinoma tissues, paraneoplastic tissues; then analyzed differences in expression normal esophageal levels overall survival Carcinoma; finally, explored We investigated tumor by infiltration functional enrichment analysis. Results: Our study revealed that was highly expressed high had worse survival. also found close positively correlated multiple cells. Conclusion: demonstrates is associated malignancy closely linked microenvironment. Furthermore, often predicts poorer features.